139 / 1084
Oesophageal CA – neo Chemoradiation or Chemo?
R
A
N
D
Primary endpoint:
Histologic complete response (pCR)
Neoadjuvant R-CTX 40,0 Gy (20 x 2Gy)
Cisplatin 100mg/m²d1 + 5FU 750mg/m² d1-5 x3
RESECTION
N=180
T1N1M0
or
T2–3N0–1M0
© Universitätsmedizin Leipzig: University Cancer Center Leipzig (UCCL), Prof. Dr. F. Lordick
Klevebro F et al.,
Ann Oncol
2016; 27: 660-667
O
M
Neoadjuvant CTX
Cisplatin 100mg/m²d1 + 5FU 750mg/m² d1-5 x3
RESECTION
AC*
SCC**
*AC: Adenocarcinoma (73%)
**SCC: Squamous cell cancer (27%)