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R

n=86

n=86

Chemotherapy

chemoradiotherapy (40 Gy)

surgery

Chemotherapy

chemoradiotherapy (>65 Gy)

2-year FFLRP 64.3% vs. 40.7%

Adding surgery to chemoradiotherapy improves local

control, but not survival (LA-SCC)

Stahl et al. J Clin Oncol 2005

p<0.003