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Response to chemotherapy / CRT
Challenges for MDCT
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Differences in luminal distension
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Lack of soft tissue contrast
•
Unable to differentiate fibrosis & tumour
Detection of response by CT:
Sensitivity: 27 – 55%; Specificity: 50 – 91%*
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*Cerfolio RJ, Bryant AS, Ohja B et al 2005. J Thorac Cardiovasc Surg; 129:1232-1241
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Swisher SG, Maish M, Erasmus JJ et al 2004. Ann Thorac Surg; 78: 1152 - 1160