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FDG-PET/CT - Response to chemotherapy / CRT
•
Metabolic response occurs early
•
Studies (eg MUNICON*) have used a reduction in the standardised
uptake value (SUV) at
14 days
•
SUV
max
reduction of
35-60%
have been shown to
correlate with pathological response
§
*Lordick F, Ott K et al. 2007 Lancet Oncol 8;9:797-805
§
Bruzzi J, Munden R et al. 2007. Radiographics 27;1635 - 1652