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Summary

The regimen of choice depends on patient-, disease- and treatment-

related factors:

• Chemoradiotherapy could be considered for patients in good condition,

with a relatively good prognosis and oligometastatic disease

• Chemotherapy could be considered for patients in relatively good

condition, with a life expectancy >6 months and metastatic disease

• EBRT is recommended for patients with a life expectancy between

three and six months, when there is no need for immediate relief

• Brachytherapy is recommended for patients with a life expectancy

between three and six months, where EBRT would take too long

• In patients with a shorter life expectancy or those with severe

dysphagia/stenosing tumor, endoscopic stent placement is preferred,

which offers instant relief of symptoms