515 / 1084
Historical Perspective
For over a century,
surgical resection
:
key modality for the treatment of EC
But
outcomes
with surgery were
poor
Taylor, H. Oesophageal carcinoma treated by resection and presternal oesophago-gastrostomy. Proc. R. Soc. Med. 1947, 40, 465–466
Garlock, J.H. Progress in the Treatment of Carcinoma of the Oesophagus and Upper Stomach. Ann. R. Coll. Surg. Engl. 1948, 2, 183–188.
Garlock, J.H. Progress in the Treatment of Carcinoma of the Oesophagus and Upper Stomach. Surgery 1948, 23, 906–911.
Earlam, R.; Cunha-Melo, J.R. Oesophageal squamous cell carcinoma: I. A critical review of surgery. Br. J. Surg.1980, 67, 381–390.
• High rates of postoperative complications
• High local and distant failure