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Historical Perspective (2)
Improve local control (LC) after surgery
postoperative radiotherapy
:
• improved LC
• patterns of failure shifted towards distant metastasis
03/01/13
• local failures were still not uncommon
The rise of radiosensitizing chemotherapy revolutionized care for EC
Scheel, A. The results of radiation treatment of esophageal cancer at Det Norske Radiumhospital.
Acta Chir. Scand.
1952
, 103, 425–429.
Davis,W.; Larionov, L.F. Progress in chemotherapy of cancer. Bull. World Health Organ.
1964
, 30, 327–341