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Ongoing trial

CALGB 80803, NCT01333033

Post-induction chemotherapy PET

choice of the chemotherapy regimen during subsequent chemoradiotherapy

followed by surgery

Preliminary report presented at the 2017 ASCO GI Cancers Symposium

- PET non responders who crossed over to an alternative chemotherapy

regimen had a higher pathologic complete response (CR) rate than did those

who continued the same regimen

Goodman KA, Niedzwiecki D, Hall N, et al. Initial results of CALGB 80803 (Alliance): A randomized phase II

trial of PET scan-directed combined modality therapy for esophageal cancer (abstract). J Clin Oncol 35, 2017

(suppl 4S; abstract 1)