39 / 96
None of the alkaloids were quantitated using this method. The scope of this method may be able
to be expanded to include quantitation because the reference standards were well characterized
nd confirmed using TLC, HPLC, IR, 1D-NMR, 2D-NMR, and ESI-High Res-MS. The
chromatographic and MS/MS conditions appear capable to allow expansion of the method’s
scope to include quantitation of the analytes.
Supporting Data
·
General Comment
N/A
Method Optimization
Method was optimized to qualitatively assess plant products and extracts for the presence
of relevant alkaloids. No quantitation of these alkaloids were presented.
·
Performance Characteristics
Analytical Range:
N/A
LOQ:
N/A
Accuracy/Recovery:
N/A
Precision (RSD
r
):
N/A
Reproducibility (RSD
R
):
N/A
System Suitibility:
N/A
Recommendation:
Do not recommend adopting this method as an AOAC OMA First Action. The method does not
meet the SMPR requirements on quiantitating the relevant alkaloids.
Reviewer:
John Szpylka
Date:
2 December 2015