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The DCE-MRI experiment
Initial T1 relaxation
1
1
=
1
1,0
+
1
1
−
with contrast agent
1,0
−
ℎ
1
−
(Relaxivity)
−
Signal dependence on flip angle and T1
Make repeated measurements with
different flip angles
Fit the equation and determine T1
T1 = 200ms
T1 = 400ms