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Summary so far
1
1
,0
,
1, 2
i
i
i
T T r C i
1
1
,0
,
1, 2
i
i
i
T T r C i
Time
Signal
C
Time
Dynamic series gives clinically relevant information
Problem: without quantitative methods the results will be:
1. Dependent on scanner
2. Dependent on sequence
3. Dependent on coils
4. Etc.
Quantitative methods rely on determination of the
contrast agent concentration
Problem: This is not easy to determine
1. Unknown relaxivity
2. Complicated relation between concentration and
signal
3. Inflow effects
4. Water exchange
5. Spoiling
6. Etc.