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What is Diffusion: Summary
Le Bihan et al., Radiology, 1988
Koh et al., AJR, 2007
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The motion of water molecules
in vivo
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In biological tissues the observed or “apparent” diffusion of water
with tissues typically <<< pure water
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Interactions with intracellular elements, membranes, and
macromolecules restrict water diffusion
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The DWI signal is derived from the motion of water molecules in the
extracellular space, the intracellular space and the intravascular space