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Diffusion weighted contrast

Gaussian distribution of diffusion

Signal

S = S

0

e

-bD

If DW signal comes from free diffusion, gradient magnetic pulse would decay DW signal

mono-exponentially with b-value

Diffusivity (-bD) decreases linearly across b-value

Diffusion coefficient is constant

b-value

D = ln(S/S

0

) / -b

D

-bD = ln(S/S

0

)

ln(S/S

0

)

b-value

b-value

Litcofsky, Pittsburg Uni