594 / 1363
Results
Group
Year N Dose
rate
Interstitial
BT (%)
LC
OS
Grade 3-
4 tox
Vienna
2011 156 HDR 44% 95% at 3 yrs 68% at 3 yrs 6%
Aarhus
2013 140 PDR 43% 91% at 3 yrs 79% at 3 yrs 7%
Pittsburg 2014 128 HDR 0%
92% at 2 yrs 88% at 2 yrs 1%
Paris
2015 225 PDR 2%
86% at 3 yrs 76% at 3 yrs 7%
Leuven
2016 154 PDR 16% 96% at 3 yrs 65% at 5 yrs 11%
Retro-
EMBRACE
2016 731 mixed 23% 91% at 3 yrs 74% at 3 yrs 11%
Conclusion: 86 – 96% local control at 2 – 3 years, with severe late toxicity ≤ 10%.