1375 / 1983
EGFR inhibitor
(antibody)
cell membrane
transcription
M
G1
G2
S
cell cycle progression
S
DS
S D
D
S
SS
SS
S
S
S
D
D
D
S
S
S
S
D
D
D
D
D
S
S
S
S
S
S
S
S
S
S
S
S
S
S
S
proliferation
angiogenesis
inhibition of apoptosis
S
SS
SS
S
S
S
D
D
D
S
S
S
S
S
metastases