1428 / 1983
Randomized trials testing new strategies for curative
treatment of head and neck cancer
Published between 2000 and 2008 in:
• N Engl J Med
• Lancet
• Lancet Oncol
• J Clin Oncol
• Int J Radiat Oncol Biol Phys
• Radiother Oncol
31/46 reported late morbidity
20/46 systematic and detailed
10/46 by actuarial method
46 studies