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Radiation Boost for Ductal Carcinoma In Situ (DCIS) After Whole

Breast Radiation Therapy (WBRT) Improves Local Control:

Collaborative Analysis of Patients Treated at Ten Academic

Institutions,

Moran MS, Zhao Y, Ma S, Kirova YM, et al, JAMA Oncol, 2017

Purpose:

To estimate the benefit of the DCIS boost

Calculate sample size needed to show this difference

To assess the independent effects of the DCIS-boost on

ipsilateral breast tumor recurrence (IBTR) in a large DCIS cohort