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Radiation Boost for Ductal Carcinoma In Situ (DCIS) After Whole

Breast Radiation Therapy (WBRT) Improves Local Control

Methods and patients:

Inclusion Criteria:

Centers with existing DCIS databases

Pure DCIS (no micro-invasion)

Treated with WBRT (no APBI)

Minimum 5 years follow-up

LR relative to clinical pathologic parameters

No brachytherapy boost (photon/electron only)

Parameters collected:

Grade, Size,Age

RT boost no boost

Moran et al, JAMA Oncol, 2017

Margin status

Comedo necrosis

ER status & Tamoxifen