1646 / 1983
GEC-ESTRO APBI trial: Treatment protocols
Control arm: Whole breast RT 50Gy +10 Gy boost
APBI CTV = tumour bed and 20 mm beyond DCIS or Ca
Pre-implant and post-implant CT mandatory
100% of dose to ≥ 90% of target and skin dose < 70%
HDR: 8 x 4Gy (BID) or 7 x 4.3Gy (BID)
Pulsed-dose-rate 50Gy / 0.6-0.8Gy x 1 per hour / 24h/day
Strnad V
et al
(2016) Lancet 387:229-238
Courtesy Chris Cottrill