592-593 / 1983
Case 2
•
Nordic study
•
291 pts; GBM; >60 yr old
•
TMZ 200mg/m2 d1-5q28 or
•
RT 60 in 30 or
•
RT 34 in 10
•
Median OS 8/12 with RT
34
or TMZ (~6/12 with RT
60
)
•
GBM >70yr old; RT
34 >OS
RT
60
•
GBM >70yr old; TMZ >
OS
RT
60
•
GBM >70yr old; RT
34
~
OS
TMZ
•
Toxicity non-zero (3 deaths ~1%TRM)
Malmstrom LancetOnc 2012