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Dosimetry: planning related data

Dose distribution

Fractionation

Volume irradiated

Hot-Cold spots

DVH (and related indicators)

Biology: OAR

Dose/Response models

(Lyman, Log-Logistic…)

Volume effect

Reliability of radiobiological prediction

Clinic: factors that can affect the outcome

Patient related: Age, Smoke, HPV status (for H&N), comorbidities…

Treatment related: chemo, hormonal therapy…

Prognosis, treatment aim (definitive, local control, palliation)

Dosimetry, Biology and Clinic

V-values

D-values

Mean dose

Maximum dose

Minimum dose