•
Dosimetry: planning related data
➢
Dose distribution
➢
Fractionation
➢
Volume irradiated
➢
Hot-Cold spots
➢
DVH (and related indicators)
•
Biology: OAR
➢
Dose/Response models
(Lyman, Log-Logistic…)
➢
Volume effect
➢
Reliability of radiobiological prediction
•
Clinic: factors that can affect the outcome
➢
Patient related: Age, Smoke, HPV status (for H&N), comorbidities…
➢
Treatment related: chemo, hormonal therapy…
➢
Prognosis, treatment aim (definitive, local control, palliation)
Dosimetry, Biology and Clinic
V-values
D-values
Mean dose
Maximum dose
Minimum dose