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Equivalent Uniform Dose
➢
The
EUD
is base on the assumption that
two dose distributions are
equivalent if they produce the same radiobiological or clinical effect
(end-point)
➢
D
j
:
the dose in the volum bin
➢
v
j
: volum bin
➢
a
: parameter that describes the serial/parallel structure of the organ
Niemierko A. A Concept of Equivalent Uniform Dose
(EUD). Volume & Kinetics in Tumor Control & Normal
Tissue Complications. 5
th
International Conference on Dose,
Time and Fractionation in Radiation Oncology. 1998
a
j
a
j
j
Dv
EUD
1
1
=
=