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Parallel
Serial
Adapted and redrawn from:
Marks LB, et al. Use of normal tissue complication probability models in
the clinic. Int. J. Radiat. Oncol. Biol. Phys. 2010 (76-3): S10-S19.
Relative
Tolerance
Dose
Fraction of
Irradiated
Volume
5
10
20
1
0.5
0
1
0.5
0.1
The Volume Effect in OAR
a
irradiated
reference
reference
irradiated
V
V
VD
VD
1
)
(
)
(
=
1/
a