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Marks LB, et al. Use of normal tissue complication probability models in the clinic.
Int. J. Radiat. Oncol. Biol. Phys. 2010 (76-3): S10-S19.
1.
a
value is function of the structure:
Spinal cord (>20)
Lung
( 1)
2.
Within a structure
a
can be function of the effect:
Rectal bleeding (Rectum)
Necrosis (Brain)
Proctitis (Rectum)
Cognitive impairment (Brain)
3. Within a structure
a
can be function of the anatomy
The Volume Effect in OAR
a
irradiated
reference
reference
irradiated
V
V
VD
VD
1
)
(
)
(
=