246 / 1161
How to consider the volume effect in
dose-response models?
•
Probit
:
Lyman
•
Logistic
(log
dose
):
Niemierko
50
4
50
1
1
+
=
D
D
NTCP
−
−
=
t
x
dx e
NTCP
2
2
2
1
(
)
2
50
50
50
−
=
D
DD
t
a
j
a
j
j
Dv
EUD
1
1
=
=