•
DVHs are based only on
anatomy
(knowledge and
interpretation) and
dose distribution
reduced to a
2D estimate
•
Dose-response model based on few geometrical
parameters could
omit clinical conditions
differentiating the patients
•
When referring
outcome prediction
on parameters
derived from literature try to compare your evaluation
to the
same conditions
used by publications
authors (if available!)
•
New methods for
patients classification
are
required to achieve a robust and reliable evaluation
Beyond the DVHs