1112 / 1416
radiosensi)ve rat yolk
sac NMT-1 tumor cell line
(
p53 wt
)
RBE = 1.41
radioresistant rat yolk sac
NMT-1R tumor cell line
(
p53 mut
)
RBE = 2.16
radiation dose (Gy)
s
u
r
v
i
v
i
n
g
fr
a
c
1
0.
1
0.0
1
1
2
3
4
Carbon ions:
No significant difference in the survival
rate
of two cell lines, regardless of
p53 status !
Bars show ± standard error where
these exceed the size of the symbol.
Par)cles: effect on cells with
inherent or aquired resistance
(Carbon Ions)