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C.P. Karger

RBE of experimental tumors

1 Fx

photons

C12

2 Fx

photons

C12

RBE

increases

with tumor progression

(H 1.6

à

HI 2.08

à

AT1 2.30 for

1fx)

Tumors possessing

highest resistance

to photons exhibit

largest RBE

Response

for 12C-ions

rather

independent

from tumor

differentiation

12C-Ionen dose response curves are generally steeper

!!!

(Glowa et al. 2015)