C.P. Karger
RBE of experimental tumors
1 Fx
photons
C12
2 Fx
photons
C12
RBE
increases
with tumor progression
(H 1.6
à
HI 2.08
à
AT1 2.30 for
1fx)
Tumors possessing
highest resistance
to photons exhibit
largest RBE
Response
for 12C-ions
rather
independent
from tumor
differentiation
12C-Ionen dose response curves are generally steeper
!!!
(Glowa et al. 2015)