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Parameter
Method Performance
Please
report in units as stated in SMPR!
Weighting
factor for
parameter
Suitability Ranking (1-
3-5)
(select from drop-down
list, 5 = best)
SPIFAN matrices
Applicable to all forms of infant, adult, and/or pediatric
formula (powders, ready-to-feed liquids, and liquid
concentrates).
Any combination of milk, soy, rice, whey, hydrolyzed
protein, starch, and amino acids, with and without intact
protein.
1
All analytes defined in the
applicability statement are
measured.
1
5-200 µg/100g
13.6-1360 µg/100 g
Fluoride
Not provided
1.77 µg/100 g
Fluoride
Not provided
5.86 µg/100 g
Spike recovery (%) (5-25µg/100g): 80–120%; (26-200µg/100g): 90–110%
88.6% (spiked level1), 104.8% (spiked level2)
2
Bias vs SRM
SRM value not provided
SRM value not provided
3
(5-25µg/100g) ≤ 8%; (26-200µg/100g) ≤5%
0.60%
Not provided
(5-25µg/100g) ≤ 15%; (26-200µg/100g) ≤10%
11.50%
b
Units
Bias against established method
Analytical equipment
1
Adequate proof of performance via system suitability
Is there a bias Yes/No ? No certified value provided in SMPR
Analytical equipment is commonly available in most labs.
3
1
2
a
Concentrations apply to (1) "ready to feed liquids" "as-is"; (2) reconstituted powders (1.47 g into 20 g water); and (3) liquid concentrates diluted (5g in 20g water).
Did Method Author Consider ERP’s Method Specific
Recommendations
(See web link to specific method
comments):
Decision by ERP
Proprietary equipment
move to Final Action/repeal/remove/expand 2 year term
0
No unique proprietary equipment/accessories are required.
Method does not require any special safety precautions e.g. personal protection from highly toxic solvents.
Notes:
Overall Score
Recommendation of ERP
2 years after First Action Status
Laboratory safety
Evaluation of Method Performance vs. SMPR requirements.
Feedback from Users of the Method since being awarded
First Action
Official Methods
Status
Repeatability (RSDr)
Reproducibility (RSDR)
Accuracy/Recovery
ADDITIONAL EVALUATION PARAMETERS
AOAC SMPR: 2014.016
Limit of detection (LOD)
1
Intermediate Reproducibility
(RSDiR)
Other Considerations
Limit of quantification (LOQ)
Method Reference #
2014.016
Method title:
Principle of the method:
Single Laboratory Validation for Fluoride Analysis in Infant Formula and Adult Nutritionals: AOAC SMPR 2014.016
Ion Chromatography with suppressed conductivity detection
SMPR Requirement
Analytical Range.
1
SPIFAN ERP Checklist v 1.6
27.06.2013
Fluor-02 - MEF FORM
FOR ERP USE ONLY
DO NOT DISTRIBUTE