793 / 1119
BT-GYN Teaching Course
D. Berger
Limitations of the EQD2 model for BT
Chemotherapy is not taken into account
Uncertainty increases for single fraction dose values >10Gy
Only cell repair is considered
α/β
values and T
1/2
are under discussion
(E.g. tumour type prostate, OAR etc.)
dose and dose rate inhomogeneity within BT volume is not
considered
Overall uncertainty of the biological dose calculation (values) in the
range of ~10% -> Reasonable rounding of values