Methods to be Reviewed by OMB in 2016

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Reddy: Journal of AOAC International Vol. 98, No. 4, 2015 1139
K. Example Calibration Curve
See Figure 2015.04F.
References
(1) J. Chromatogr. A 881, 365(2000)
(2) J. Chromatogr. A 1139, 271(2007)
(3) AOAC SMPR 2015.001 J. AOAC Int. (future issue)
min
0.50 1.00 1.50 2.00 2.50 3.00 3.50 4.00 4.50 5.00 5.50 6.00 6.50 7.00
%
0
100
MRMof2 channels,ES-
216 > 186
03121513 Smooth(Mn,2x2)
QC2
3.434e+005
MFA-2NPH_IS
4.04
min
%
0
100
MRMof2 channels,ES-
212 > 182
03121513 Smooth(Mn,2x2)
QC2
9.197e+004
MFA-2NPH
4.05
3.16
2.83 3.35
4.73 6.59
4.81 6.27
5.48 5.88
6.65
Figure 2015.04C. QC overspike Low at 25 ng/g powder.
min
0.50 1.00 1.50 2.00 2.50 3.00 3.50 4.00 4.50 5.00 5.50 6.00 6.50 7.00
%
0
100
MRMof2 channels,ES-
216 > 186
03121519 Smooth(Mn,2x2)
QC4
2.967e+005
MFA-2NPH_IS
4.04
min
%
0
100
MRMof2 channels,ES-
212 > 182
03121519 Smooth(Mn,2x2)
QC4
1.622e+006
MFA-2NPH
4.05
Figure 2015.04E. QC overspike High at 500 ng/g
powder.
II. EXAMPLE CALIBRATION CURVE SEE FIGURE XX
Compound name:MFA-2NPH
Correlation coefficient: r = 0.999397, r^2 = 0.998795
Calibration curve:0.953568 * x+ 0.0208565
Response type: Internal Std ( Ref2 ),Area * ( IS Conc. / IS Area )
Curve type:Linear,Origin:Exclude,Weighting:1/x,Axis trans:None
Conc
-0 10 20 30 40 50 60 70 80 90 100
Response
-0.0
50.0
Conc
Residual-5.0
0.0
5.0
Figure 2015.04F. Calibration curve and residual plot.
min
0.50 1.00 1.50 2.00 2.50 3.00 3.50 4.00 4.50 5.00 5.50 6.00 6.50 7.00
%
0
100
MRMof2 channels,ES-
216 > 186
03121516 Smooth(Mn,2x2)
QC3
3.304e+005
MFA-2NPH_IS
4.04
min
%
0
100
MRMof2 channels,ES-
212 > 182
03121516 Smooth(Mn,2x2)
QC3
3.995e+005
MFA-2NPH
4.05
4.81 6.58
6.27
Figure 2015.04D. QC overspike Med at 100 ng/g powder.
Candidates for 2016 Method of the Year
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