ERP Proposal SPDS Set 2

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questions around the testing. Recently, during the working group meetings, I did some additional work for the
working group in order to help decide the scope of the SMPR with various standard materials.
FULL CV:
KRUEGER, DANA
Area of Expertise: Folin-C
My lab has used the Folin-Ciocalteu phenolics method for more than 20 years, particularly with reference to phenolics
analysis of beverages
FULL CV:
LEE, JUNGMIN
Area of Expertise: Total Phenolics/FolinC
I have working knowledge of Folin-Ciocalteu (also known as total phenolics; AOAC abbreviated as Folin-C) method and
published numerous papers using this method as indicated in my accompanying CV.
FULL CV:
METCALFE, CHARLES
Area of Expertise: Kratom
We have been analyzing Kratom raw materials and finished products for over 2 years. Initially we ran samples by
conventional HPLC with a run time of 30 minutes. We found this run time to be unacceptable due to the number of
samples we were required to assay. Our new methodology utilized UHPLC with a reduced run time of less than 8
minutes. All of the relevant alkaloids are separated. Althought the 7-OH mitragynine is of the most interest to
regulatory agencies, we have yet to find any of this isomer in either raw materials or finished products. A sample
chromatogram of our new assay is attached.
FULL CV:
PHILLIPS, TOM
Area of Expertise: Various Methodologies
I have over 20 years Mass Spectrometry experience; ten of which are with hyphenated techniques, i.e., ms/ms, bot
GC and LC. I have over 4 years of experience with herbal products, both the raw material and the finished products. I
have developed in-house method for the determination of actives in herbals, but I do not have experience with these
particular ones. I have done Folin C in several matrices for about 5 years or so.
FULL CV:
RIMMER, CATHERINE
Area of Expertise: Various Methodologies
My experience is with the methodologies (especially chromatography, absorption detection, fluorescence detection
and mass spectrometric detection) and the statistics utilized for quantitation and qualitative identity testing. As the
dietary supplement program coordinator at NIST, I keep up on dietary supplement matricies, analytes, and methods.
FULL CV:
SAYRE, CASEY
Area of Expertise: instrumentation and botanicals; method development & validation
I have experience with some of the instruments and techniques that could be used to detect or determine the
ingredients in the call for experts. These include HPLC, mass spectrometry, and UV spectrophotometry. Additionally, I
have experience with botanical sample extraction and preparation for quantitative analysis. I also have experience in
the development and validation of stereospecific quantitative methods of detection of plant secondary metabolites in
aglycone and glycoside forms. Most of the analytes I have experience with are chiral polyphenols.
FULL CV: