1658-1659 / 2001
Radiother Oncol.
2014 Feb;110(2):213-228.
Second primary cancers after radiation for prostate cancer: A systematic review of
the clinical data and impact of treatment technique.
Murray L
1
,
Henry A
2
,
Hoskin P
3
,
Siebert FA
4
,
Venselaar J
5
;
PROBATE group of the GEC
ESTRO
.
To date there are insufficient clinical data to draw firm
l i
b h i
f
d
conc us ons a out t e mpact o more mo ern
techniques such as IMRT and brachytherapy on SPC
risk although limited evidence is encouraging
,
.
In conclusion despite heterogeneity between studies
,
,
an increased risk of SPC following radiation for PCa has
been identified in several studies, and this risk appears
to increase over time. This must be borne in mind when
considering which patients to irradiate and which
h i
l
tec n ques to emp oy.