1662-1663 / 2001
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Int J Radiat Oncol Biol Phys.
2015 Feb 1;91(2):295-302.
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Risk of second cancers according to radiation therapy technique
and modality in prostate cancer survivors.
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Berrington de Gonzalez A
1
,
Wong J
2
,
Kleinerman R
2
,
Kim C
2
,
Morton L
2
,
Bekelman JE
3
.
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Author information
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, National Cancer Institute, National Institutes of Health, Bethesda, Maryland. Electronic address:
berringtona@mail.nih.gov.•
METHODS AND MATERIALS:
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The cohort was constructed using the Surveillance Epidemiology and End Results-Medicare
database. We included cases of prostate cancer diagnosed in patients 66 to 84 years of age from
1992 to 2004 and followed through 2009.
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RESULTS:
D i
f 4 4 ' f ll
5
t t
i
2933 d
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ur ng an average o . years o ow-up among -year pros a e cancer surv vors …
secon
solid cancers were diagnosed. …
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Rates of second solid cancers for higher- and lower-energy RT were similar overall (RR = 0.97,
95% CI: 0.89-1.06), as were rates for site-specific cancers.
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There were significant reductions in colon cancer and leukemia
rates in the first decade after brachytherapy compared to those
after external beam RT.
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