93 / 208
Evidence for the use of PN in the PICU
91
5
search, 8 articles were retained
10-17
. Of these, full text reading resulted in exclusion of another
2 articles, one that was related to EN instead of PN and one was not a RCT
15,16
. Table 1 gives
an overview of the 6 trials, of which 1 was a post-hoc analysis of one of 5 RCTs
11
, that were
identified as relevant for this review. As the retained studies used different interventions and
outcome measures they could not be analyzed in a formal meta-analysis.
MEDLINE
213 articles
NICU
17
Not PN related 247
Not PICU related
31
Adult population
15
Study on glycemic control
3
Adult population 33
NICU 18
Descriptive studies 31
Review 24
114 articles
8 articles
6 articles
No RCT 1
Not PN related 1
Text screening
EMBASE
468 articles
584 articles
Hand search
2 articles
Duplicates
99
Title screening
Abstract screening
Figure 1.
Flowchart of screening process
NICU=Neonatal Intensive Care Unit, PN=Parenteral Nutrition, RCT=Randomized Controlled Trial