SPDS 09052014 - page 222

Effect of Sensoril® on Cold Pressor-induced
Change in Augmentation Index
Mean % Change in Augmentation Index Induced by
Cold Pressor Test with Sensoril
®
& Placebo
entation Index
n % Change
31
CONFIDENTIAL
Augm
Mea
Data Expressed as Mean ± SD
***p<0.001 Compared to Pretreatment
***
Effect of Sensoril® on Mental Stress-induced
Cardiovascular Changes in
Healthy Volunteers
Study Design: Randomized, double-blind, placebo-
controlled, crossover
Subjects: 20 healthy male subjects
Dosage: 2 x Sensoril® 250mg BID
2 x Matching placebo capsules BID
Duration of treatment: 2 weeks
32
CONFIDENTIAL
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