SPDS 09052014 - page 225

Effect of Sensoril® on Pain Threshold Force and
Threshold Time in
Healthy Volunteers
Mechanical Pain Model
Placebo
Sensoril
®
p value
Baseline threshold force
(grams)
443.06
±
65.02 450.3
±
75.49 ns
Post Drug threshold force
(grams)
446.53
±
65.95 538.5
±
72.27 <0.05
Baseline threshold Time
(seconds)
5.54 ± 0.81 5.62 ± 0.94
ns
Post Drug threshold Time
(seconds)
5.58 ± 0.82 6.73 ± 0.90 <0.05
All values - Mean ± Standard deviation
p values represent the students paired t test between
the placebo and Sensoril
®
group
Effect of Sensoril® on Pain Threshold Time
Healthy Volunteers
Hot Air Pain Model
80
100
20
40
60
Time in seconds
baseline
postdrug
p<0.001
$
p-ns*
43.79 ± 6.79
43.99 ± 6.93
44.28 ± 9.19
49.89 ± 7.07
0
Placebo
Sensoril
Values given as Mean ± SD
* compared to baseline
$ compared to baseline and placebo
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