Effect of Sensoril® on Psychomotor
Performance in
Healthy Volunteers
Study Design: Randomized, double-blind, placebo-
ll d
contro e , crossover
Subjects: 20 healthy male subjects
Dosage: 2 x Sensoril® 250mg BID
2 x Matching placebo capsules BID
35
CONFIDENTIAL
Duration of treatment: 2 weeks
Effect of Sensoril® on Psychomotor
Performance in
Healthy Volunteers
Test
Reaction Time with Sensoril®, ms Reaction Time with Placebo, ms
Pre Treatment Post Treatment
Pre Treatment
Post Treatment
Finger tapping
187±16
183±17 (ns)
192±14
194±14 (ns)
Simple reaction test
306±39
287±43 **
313±45
316±26 (ns)
Choice discrimination
test
471±34
455±51 *
476±34
477±30 (ns)
Digit Symbol
Substitution Test
1695±263
1557±233 **
1690±279
1739±313 (ns)
Digit vigilance task
1360±57
1317±88 **
1371±79
1395±82 (ns)
Card sorting test
96±19
84±13 *
98±17
98±20 (ns)
P value compared to baseline in Reaction Time
36
CONFIDENTIAL
ns – Not significant; * p<0.05; ** p<0.001
