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Hematopoietic stem cell transplant (HSCT)
• HSCT: The transfer of hematopoietic stem cells
(HSCs) between a donor and a recipient
– HSCs are often referred to as “graft”
– Successful transfer of HSCs requires “conditioning”
recipient, otherwise rejection will occur
• Myeloablative: capable of completely eliminating recipient
blood system (lethal)
• Non-myeloablative: not capable of completely eliminating
recipient blood system (non-lethal)