557 / 1835
►
Improvement in EFS, PFS and OS
►
Outcome of R-CHOP x 8 arm inferior to those observed in MInT with
R-CHOP x 6
►
Excess utilisation of healthcare resource
►
Excess of toxicity
Recher C
, et al Lancet
2011: 378:1858-1867.
R-ACVBP
R-CHOP
Toxicity (grade >3)
Neutropenia
78%
64%
Anemia
35%
5%
Thrombocytopenia
30%
3%
Febrile neutropenia
38%
9%
Toxic deaths (n)
3
2