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GEP can now be reliably be performed
using FFPE tissue – Illumina DASL
array, allow for use of partially
degraded RNA (spans short
sequence).
Derived from multiple sample sets
Algorithm allowing classification
sample by sample, week on week
Cross platform validation; correlates
with predicted mutation profile
Outcomes in validated in population
based analysis
Transcriptome analysis: DLBCL automatic
classifier
Barrans SL,
et al. Brit J Haematol
2012 159 (4) 441-453
Care M, et al. PLoS ONE 8(2) : e55895