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Treatments approaches for those requiring

treatment (high tumour burden)

General approach : rituximab and ……

alkylating agents +/- anthracycline

Bendamustine / Purine analogues

alternative non chemotherapy options

Radioimmunotherapy

Lenalidomide and rituximab

New generation anti-CD20 antibodies (Ofatumumab, GA101

[Obinutuzumab]).