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Rituximab-Chemotherapy in
Untreated Advanced Follicular NHL
Study
Treatment, n
Median
FU,
months
ORR,
%
CR,
%
Median TTP/
TTF/ EFS,
mo
OS,
%
Marcus
et al. 2008
CVP, 159
R-CVP, 162
53
57
81
10
41
15
34
P
<.0001
77
83
P
=.0290
Hiddemann
et al. 2005
CHOP-IFN, 205
R-CHOP-IFN, 223
18
90
96
17
20
29
NR
P
<.001
90
95
P
=.016
Herold
et al. 2007
MCP-IFN, 96
R-MCP-IFN, 105
47
75
92
25
50
26
NR
P
<.0001
74
87
P
=.0096
Salles
et al. 2008
CHVP-IFN, 183
R-CHVP-IFN, 175
42
73
84
63
79
46
67
P
<.0001
84
91
P
=.029