2016 Hematological Malignancies

StiL R-Benda vs R-CHOP

Rummel MJ et al : Lancet Feb 20, 2013

B-R

n = 261

CHOP-R

n = 253

Median age, years (range)

64 (34–83)

63 (31–82)

B-symptoms

100 (38)

74 (29)

Ann Arbor stage III/IV, n (%)

252 (96)

244 (97)

Lactate dehydrogenase > ULN, n (%)

100 (38)

84 (33)

Histology n (%)

Follicular

139 (53)

140 (55)

Mantle cell

46 (18)

48 (19)

Lymphoplasmacytic

22 (8)

19 (8)

SLL

10 (4)

11 (4)

High-risk FLIPI, n (%)

63 (46)

64 (48)

• No observed differences between the two study arms