Cancer genome sequencing
• >25,000 whole cancer genomes have been
sequenced per Feb 27
th
2016
• Total # somatic mutations per individual tumor:
Medulloblastoma
Testicular germline
Acute leukemia
Carcinoids
Breast
Ovary
Colorectal
Pancreas
Glioma
Lung
Melanoma
10
2
10
3
10
4
10
5
From Stratton, Science 2011
And COSMIC