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Cancer genome sequencing

• >25,000 whole cancer genomes have been

sequenced per Feb 27

th

2016

• Total # somatic mutations per individual tumor:

Medulloblastoma

Testicular germline

Acute leukemia

Carcinoids

Breast

Ovary

Colorectal

Pancreas

Glioma

Lung

Melanoma

10

2

10

3

10

4

10

5

From Stratton, Science 2011

And COSMIC