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0

2

4

6

8 10 12

Dose (Gy)

0.001

0.01

0.1

1

Surviving fraction

SC69

U2

SQD9

A549

A1847

SCC61

MCF7

Biological contributors to outcome of tumor

treatment with radiation

Proliferation

Hypoxia

Vascular

Radiosensitivity?

Tumor cell

radiosensitivity

Volume

(Stem cell proportion)