1166 / 1816
ER-positive disease and tamoxifen
• Tamoxifen for 1-2 years is significantly more effective than no treatment
•
Recurrence rate 5,8% vs 7,1%/year
• Tamoxifen for 5 years is significantly more effective than just 1–2 years of
tamoxifen.
• 5 year of adjuvant tamoxifen reduces the annual breast cancer death rate
by 31% (SE 3)
•
Irrespective of the use of chemotherapy and of age, progesterone
receptor status, or other tumor characteristics.
19-9-2017
EBCTCG 2005 & 2011