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Aromatase inhibitors (AI)
Upfront studies: AI versus tamoxifen (5 year)
ATAC; BIG 1-98; ABCSG-12
Sequential studies
2-3 y tamoxifen followed by 3-2y AI vs 5y tamoxifen or 5y AI
2-3 y AI followed by 3-2y tamoxifen vs 5y tamoxifen or 5y AI
IES; ITA; ARNO-95 Randomisation after 2-3y tamoxifen
TEAM; ABCSG-8
Extension studies
AI after 5y tamoxifen
AI after 5y tamoxifen/AI
MA.17; ABCSG-6A; NSABP B-33; DATA; LEAD
19-9-2017