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Conundrum of PST: current evidence
Mamounas E, et al. JCO 2012;30:3960-6.
Combined analysis of NSABP B18 and B27
Predictors of LRR after primary chemotherapy
Follow-up 10 years:
•
335 LRR events
•
10 year cumulative incidence of LRR:
•
12.3% (local 8.9%, regional 3.4%) for mastectomy
•
10.3% (local 8.1%, regional 2.2%) for BCS + radiation